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Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage

Nitric oxide (NO(•)) is thought to protect against the damaging effects of myocardial ischemia–reperfusion injury, whereas xanthine oxidoreductase (XOR) normally causes damage through the generation of reactive oxygen species. In the heart, inorganic nitrite [Formula: see text] has the potential to...

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Autors principals: Webb, Andrew, Bond, Richard, McLean, Peter, Uppal, Rakesh, Benjamin, Nigel, Ahluwalia, Amrita
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC518813/
https://ncbi.nlm.nih.gov/pubmed/15347817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402927101
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