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Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage

Nitric oxide (NO(•)) is thought to protect against the damaging effects of myocardial ischemia–reperfusion injury, whereas xanthine oxidoreductase (XOR) normally causes damage through the generation of reactive oxygen species. In the heart, inorganic nitrite [Formula: see text] has the potential to...

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Autori principali: Webb, Andrew, Bond, Richard, McLean, Peter, Uppal, Rakesh, Benjamin, Nigel, Ahluwalia, Amrita
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC518813/
https://ncbi.nlm.nih.gov/pubmed/15347817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402927101
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