NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

The NF-κB/IκB signaling pathway is a critical regulator of cell survival in cancer. Here, we report that combined down-regulation of growth arrest- and DNA-damage-inducible proteins (GADD)45α and γ expression by NF-κB is an essential step for various cancer types to escape programmed cell death. We...

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Detalhes bibliográficos
Main Authors: Zerbini, Luiz F., Wang, Yihong, Czibere, Akos, Correa, Ricardo G., Cho, Je-Yoel, Ijiri, Kosei, Wei, Wanjang, Joseph, Marie, Gu, Xuesong, Grall, Franck, Goldring, Mary B., Zhou, Jin-Rhong, Libermann, Towia A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518803/
https://ncbi.nlm.nih.gov/pubmed/15353598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402069101
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