Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals

Neuronal death is often preceded by functional alterations at nerve terminals. Anti- and proapoptotic BCL-2 family proteins not only regulate the neuronal death pathway but also affect excitability of healthy neurons. We found that exposure of squid stellate ganglia to hypoxia, a death stimulus for...

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Библиографические подробности
Главные авторы: Jonas, Elizabeth A., Hickman, John A., Chachar, Mushtaque, Polster, Brian M., Brandt, Teresa A., Fannjiang, Yihru, Ivanovska, Iva, Basañez, Gorka, Kinnally, Kathleen W., Zimmerberg, Joshua, Hardwick, J. Marie, Kaczmarek, Leonard K.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC518799/
https://ncbi.nlm.nih.gov/pubmed/15342906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401372101
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