Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals

Neuronal death is often preceded by functional alterations at nerve terminals. Anti- and proapoptotic BCL-2 family proteins not only regulate the neuronal death pathway but also affect excitability of healthy neurons. We found that exposure of squid stellate ganglia to hypoxia, a death stimulus for...

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Detaylı Bibliyografya
Asıl Yazarlar: Jonas, Elizabeth A., Hickman, John A., Chachar, Mushtaque, Polster, Brian M., Brandt, Teresa A., Fannjiang, Yihru, Ivanovska, Iva, Basañez, Gorka, Kinnally, Kathleen W., Zimmerberg, Joshua, Hardwick, J. Marie, Kaczmarek, Leonard K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC518799/
https://ncbi.nlm.nih.gov/pubmed/15342906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401372101
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