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The Emergence of the Dose–Response Concept in Biology and Medicine
A historical assessment of the origin of the dose–response in modern toxicology and its integration as a central concept in biology and medicine is presented. This article provides an overview of how the threshold, linear and biphasic (i.e., hormetic) dose–response models emerged in the late 19th an...
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Publicado en: | Int J Mol Sci |
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Autor principal: | |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5187834/ https://ncbi.nlm.nih.gov/pubmed/27929392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17122034 |
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