Fast folding of a helical protein initiated by the collision of unstructured chains
To examine whether helix formation necessarily precedes chain collision, we have measured the folding of a fully helical coiled coil that has been specially engineered to have negligible intrinsic helical propensity but high overall stability. The folding rate approaches the diffusion-limited value...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC518782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15347811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404057101 |
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