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Rapid induction of heme oxygenase 1 mRNA and protein by hyperthermia in rat brain: heme oxygenase 2 is not a heat shock protein.

Catalytic activity of heme oxygenase (heme, hydrogen-donor:oxygen oxidoreductase, EC 1.14.99.3) isozymes, HO-1 and HO-2, permits production of physiologic isomers of bile pigments. In turn, bile pigments biliverdin and bilirubin are effective antioxidants in biological systems. In the rat brain we h...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ewing, J F, Maines, M D
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2052613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5364
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