Molecular Chaperones’ Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a neuronal degenerative condition identified via a build-up of mutant aberrantly folded proteins. The native folding of polypeptides is mediated by molecular chaperones, preventing their pathogenic aggregation. The mutant protein expression in ALS is linked wit...

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主要な著者:	Sumit Kinger, Ankur Rakesh Dubey, Prashant Kumar, Yuvraj Anandrao Jagtap, Akash Choudhary, Amit Kumar, Vijay Kumar Prajapati, Rohan Dhiman, Amit Mishra
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2023-05-01
シリーズ:	Cells
主題:	ALS chaperones HSP70 HSP27 HSPB8 HSP40
オンライン･アクセス:	https://www.mdpi.com/2073-4409/12/9/1302
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