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Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control

The mitochondrial contact site and cristae organizing system (MICOS) and Optic atrophy 1 (OPA1) control cristae shape, thus affecting mitochondrial function and apoptosis. Whether and how they physically and functionally interact is unclear. Here, we provide evidence that OPA1 is epistatic to MICOS...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Glytsou, Christina, Calvo, Enrique, Cogliati, Sara, Mehrotra, Arpit, Anastasia, Irene, Rigoni, Giovanni, Raimondi, Andrea, Shintani, Norihito, Loureiro, Marta, Vazquez, Jesùs, Pellegrini, Luca, Enriquez, Jose Antonio, Scorrano, Luca, Soriano, Maria Eugenia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5186903/
https://ncbi.nlm.nih.gov/pubmed/27974214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.049
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