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Kinetics of protective antibodies are determined by the viral surface antigen

Delayed and weak virus neutralizing antibody (nAb) responses represent a hallmark correlating not only with the establishment of persistent infection but also with unsuccessful vaccine development. Using a reverse genetic approach, we evaluated possible underlying mechanisms in 2 widely studied vira...

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Publicado no:J Clin Invest
Principais autores: Pinschewer, Daniel D., Perez, Mar, Jeetendra, Eswaraka, Bächi, Thomas, Horvath, Edit, Hengartner, Hans, Whitt, Michael A., de la Torre, Juan Carlos, Zinkernagel, Rolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC518669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15467838/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI22374
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