Kinetics of protective antibodies are determined by the viral surface antigen

Delayed and weak virus neutralizing antibody (nAb) responses represent a hallmark correlating not only with the establishment of persistent infection but also with unsuccessful vaccine development. Using a reverse genetic approach, we evaluated possible underlying mechanisms in 2 widely studied vira...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Pinschewer, Daniel D., Perez, Mar, Jeetendra, Eswaraka, Bächi, Thomas, Horvath, Edit, Hengartner, Hans, Whitt, Michael A., de la Torre, Juan Carlos, Zinkernagel, Rolf M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 2004
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC518669/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15467838/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI22374
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