Molecular mechanism of slow acetylation of drugs and carcinogens in humans.
The acetylation polymorphism is one of the most common genetic variations in the transformation of drugs and chemicals. More than 50% of individuals in Caucasian populations are homozygous for a recessive trait and are of the "slow acetylator" phenotype. They are less efficient than "rapid acetylato...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1991
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1675794/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5237 |
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