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Expanding the Repertoire of Carbapenem-Hydrolyzing Metallo-ß-Lactamases by Functional Metagenomic Analysis of Soil Microbiota

Carbapenemases are bacterial enzymes that hydrolyze carbapenems, a group of last-resort β-lactam antibiotics used for treatment of severe bacterial infections. They belong to three β-lactamase classes based amino acid sequence (A, B, and D). The aim of this study was to elucidate occurrence, diversi...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Gudeta, Dereje D., Bortolaia, Valeria, Pollini, Simona, Docquier, Jean-Denis, Rossolini, Gian M., Amos, Gregory C. A., Wellington, Elizabeth M. H., Guardabassi, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5184135/
https://ncbi.nlm.nih.gov/pubmed/28082950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01985
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