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Lipidomic profiling of high-fat diet-induced obesity in mice: importance of cytochrome P450-derived fatty acid epoxides

OBJECTIVE: Enzymatic metabolism of polyunsaturated fatty acids (PUFAs) leads to formation of bioactive lipid metabolites (LMs). Previous studies have shown that obesity leads to deregulation of LMs in adipose tissues. However, most previous studies have focused on single or limited number of LMs, fe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Obesity (Silver Spring)
Hauptverfasser: Wang, Weicang, Yang, Jun, Qi, Weipeng, Yang, Haixia, Wang, Chang, Tan, Bowen, Hammock, Bruce D., Park, Yeonhwa, Kim, Daeyoung, Zhang, Guodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182168/
https://ncbi.nlm.nih.gov/pubmed/27891824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21692
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