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Increased Brain Lactate during Depressive Episodes and Reversal Effects by Lithium Monotherapy in Drug-Naive Bipolar Disorder: A 3T 1H-MRS Study
OBJECTIVE: Mitochondrial dysfunction and energy metabolism impairment are key components in the pathophysiology of bipolar disorder (BD) and may involve a shift from aerobic to anaerobic metabolism. Measurement of brain lactate in vivo using proton magnetic resonance spectroscopy (1H-MRS) represents...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Clin Psychopharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182117/ https://ncbi.nlm.nih.gov/pubmed/27902528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0000000000000616 |
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