Lithium increases nitric oxide levels in subjects with bipolar disorder during depressive episodes

BACKGROUND: Altered nitric oxide (NO) signaling has been associated with the pathophysiology of Bipolar Disorder (BD), directly affecting neurotransmitter release and synaptic plasticity cascades. Lithium has shown to regulate NO levels in preclinical models. However, no study has addressed peripher...

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Hauptverfasser: de Sousa, Rafael T., Zanetti, Marcus V., Busatto, Geraldo F., Mouro, Margaret G., Zarate, Carlos A., Gattaz, Wagner F., Higa, Elisa M., Machado-Vieira, Rodrigo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084566/
https://ncbi.nlm.nih.gov/pubmed/24768108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2014.03.023
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