A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp

Proliferating cell nuclear antigen (PCNA) forms a trimeric ring that encircles duplex DNA and acts as an anchor for a number of proteins involved in DNA metabolic processes. PCNA has two structurally similar domains (I and II) linked by a long loop (inter-domain connector loop, IDCL) on the outside...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Altieri, Amanda S., Ladner, Jane E., Li, Zhuo, Robinson, Howard, Sallman, Zahur F., Marino, John P., Kelman, Zvi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181682/
https://ncbi.nlm.nih.gov/pubmed/27141962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw351
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