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Oxidative metabolism and Ca(2+) handling in isolated brain mitochondria and striatal neurons from R6/2 mice, a model of Huntington’s disease
Alterations in oxidative metabolism and defects in mitochondrial Ca(2+ )handling have been implicated in the pathology of Huntington’s disease (HD), but existing data are contradictory. We investigated the effect of human mHtt fragments on oxidative metabolism and Ca(2+ )handling in isolated brain m...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Hum Mol Genet |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5181640/ https://ncbi.nlm.nih.gov/pubmed/27131346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw133 |
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