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Predicting G protein-coupled receptor downstream signaling by tissue expression

Motivation: G protein-coupled receptors (GPCRs) are central to how cells respond to their environment and a major class of pharmacological targets. However, comprehensive knowledge of which pathways are activated and deactivated by these essential sensors is largely unknown. To better understand the...

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Библиографические подробности
Опубликовано в: :Bioinformatics
Главные авторы: Hao, Yun, Tatonetti, Nicholas P.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181570/
https://ncbi.nlm.nih.gov/pubmed/27485444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw510
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