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An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins.

Two forms of FosB transcript and their products can be identified in mouse NIH 3T3 cells following serum induction. The larger RNA codes for a 338-amino acid protein, whereas the smaller RNA results from the removal of an additional 140 nucleotides from FosB mRNA by alternative splicing. This altern...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Yen, J, Wisdom, R M, Tratner, I, Verma, I M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5077
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