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An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins.

Two forms of FosB transcript and their products can be identified in mouse NIH 3T3 cells following serum induction. The larger RNA codes for a 338-amino acid protein, whereas the smaller RNA results from the removal of an additional 140 nucleotides from FosB mRNA by alternative splicing. This altern...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yen, J, Wisdom, R M, Tratner, I, Verma, I M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.12.5077
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