Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis: a retrospective observational cohort study of the Mycoses Study Group (MSG-12)

OBJECTIVES: A polymorphism in the gene encoding β-1,3-glucan synthase, the target of the echinocandin class of antifungals, results in increased in vitro MICs of the echinocandins. This has resulted in controversy surrounding use of the echinocandins for treatment of Candida parapsilosis candidaemia...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Chiotos, Kathleen, Vendetti, Neika, Zaoutis, Theoklis E., Baddley, John, Ostrosky-Zeichner, Luis, Pappas, Peter, Fisher, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181395/
https://ncbi.nlm.nih.gov/pubmed/27494929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw305
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