Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis: a retrospective observational cohort study of the Mycoses Study Group (MSG-12)

OBJECTIVES: A polymorphism in the gene encoding β-1,3-glucan synthase, the target of the echinocandin class of antifungals, results in increased in vitro MICs of the echinocandins. This has resulted in controversy surrounding use of the echinocandins for treatment of Candida parapsilosis candidaemia...

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Detalles Bibliográficos
Publicado en:J Antimicrob Chemother
Autores principales: Chiotos, Kathleen, Vendetti, Neika, Zaoutis, Theoklis E., Baddley, John, Ostrosky-Zeichner, Luis, Pappas, Peter, Fisher, Brian T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181395/
https://ncbi.nlm.nih.gov/pubmed/27494929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw305
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