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Computational analysis of EBNA1 “druggability” suggests novel insights for Epstein-Barr virus inhibitor design
The Epstein-Barr Nuclear Antigen 1 (EBNA1) is a critical protein encoded by the Epstein-Barr Virus (EBV). During latent infection, EBNA1 is essential for DNA replication and transcription initiation of viral and cellular genes and is necessary to immortalize primary B-lymphocytes. Nonetheless, the c...
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| Udgivet i: | J Comput Aided Mol Des |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5180362/ https://ncbi.nlm.nih.gov/pubmed/27048620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-016-9899-y |
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