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Development of a High-Throughput Screen for Inhibitors of Epstein-Barr Virus EBNA1

Latent infection with Epstein-Barr Virus (EBV) is a carcinogenic cofactor in several lymphoid and epithelial cell malignancies. At present, there are no small molecule inhibitors that specifically target EBV latent infection or latency-associated oncoproteins. EBNA1 is an EBV-encoded sequence-specif...

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Détails bibliographiques
Auteurs principaux: Thompson, Scott, Messick, Troy, Schultz, David C., Reichman, Melvin, Lieberman, Paul M.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310380/
https://ncbi.nlm.nih.gov/pubmed/20930215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057110379154
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