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Class B β-arrestin2-dependent CCR5 signalosome retention with natural antibodies to CCR5
CCR5 stimulation with natural ligands, such as RANTES, classically induces short-term internalization with transient activation of β-arrestins and rapidly recycling on the cell surface. Here we discovered that, in T cells, natural CCR5 antibodies induce a CCR5-negative phenotype with the involvement...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5180096/ https://ncbi.nlm.nih.gov/pubmed/28008933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39382 |
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