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Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro.

The response of endothelial cells to angiogenic stimuli has been shown to be influenced by the extracellular microenvironment. We tested whether thrombospondin, an extracellular matrix protein, modulated the spontaneous formation of cords by endothelial cells in vitro. Despite continued proliferatio...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Iruela-Arispe, M L, Bornstein, P, Sage, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1991
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51800/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1711216/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.11.5026
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