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A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

A secreted inhibitor of angiogenesis that is controlled by a tumor suppressor gene in hamster cells has been found to be similar to a fragment of the platelet and matrix protein thrombospondin. The two proteins were biochemically similar and immunologically crossreactive and could substitute for one...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Good, D J, Polverini, P J, Rastinejad, F, Le Beau, M M, Lemons, R S, Frazier, W A, Bouck, N P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54589/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.17.6624
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