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Rescue of neural crest-derived phenotypes in a zebrafish CHARGE model by Sox10 downregulation
CHD7 mutations are implicated in a majority of cases of the congenital disorder, CHARGE syndrome. CHARGE, an autosomal dominant syndrome, is known to affect multiple tissues including eye, heart, ear, craniofacial nerves and skeleton and genital organs. Using a morpholino-antisense-oligonucleotide-b...
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Publicado no: | Hum Mol Genet |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5179949/ https://ncbi.nlm.nih.gov/pubmed/27418670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw198 |
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