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Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase

Transforming growth factor-beta (TGF-β) is a multi-functional cytokine implicated in the control of cell growth and differentiation. TGF-β signals through a complex of TGF-β receptors 1 and 2 (TGFβR1 and TGFβR2) that phosphorylate and activate Smad2/3 transcription factors driving transcription of t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: La, Jennifer, Reed, Eleanor, Chan, Lan, Smolyaninova, Larisa V., Akomova, Olga A., Mutlu, Gökhan M., Orlov, Sergei N., Dulin, Nickolai O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179089/
https://ncbi.nlm.nih.gov/pubmed/28006004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168363
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