CGG Repeats in the 5’UTR of FMR1 RNA Regulate Translation of Other RNAs Localized in the Same RNA Granules

CGG repeats in the 5’UTR of Fragile X Mental Retardation 1 (FMR1) RNA mediate RNA localization and translation in granules. Large expansions of CGG repeats (> 200 repeats) in FMR1, referred to as full mutations, are associated with fragile X syndrome (FXS). Smaller expansions (55–200 repeats), re...

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Publicat a:PLoS One
Autors principals: Rovozzo, René, Korza, George, Baker, Mei W., Li, Meng, Bhattacharyya, Anita, Barbarese, Elisa, Carson, John H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179066/
https://ncbi.nlm.nih.gov/pubmed/28005950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168204
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