CGG Repeats in the 5’UTR of FMR1 RNA Regulate Translation of Other RNAs Localized in the Same RNA Granules

CGG repeats in the 5’UTR of Fragile X Mental Retardation 1 (FMR1) RNA mediate RNA localization and translation in granules. Large expansions of CGG repeats (> 200 repeats) in FMR1, referred to as full mutations, are associated with fragile X syndrome (FXS). Smaller expansions (55–200 repeats), re...

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Опубликовано в: :PLoS One
Главные авторы: Rovozzo, René, Korza, George, Baker, Mei W., Li, Meng, Bhattacharyya, Anita, Barbarese, Elisa, Carson, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179066/
https://ncbi.nlm.nih.gov/pubmed/28005950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168204
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