Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis

Cardiac mitochondrial function is altered in a variety of inherited and acquired cardiovascular diseases. Recent studies have identified the transcriptional coactivator peroxisome proliferator–activated receptor γ coactivator-1 (PGC-1) as a regulator of mitochondrial function in tissues specialized...

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Main Authors: Lehman, John J., Barger, Philip M., Kovacs, Attila, Saffitz, Jeffrey E., Medeiros, Denis M., Kelly, Daniel P.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC517815/
https://ncbi.nlm.nih.gov/pubmed/11018072
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