Bmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer

We recently reported that the polycomb complex protein Bmi1 is a marker for lingual epithelial stem cells (LESCs), which are involved in the long-term maintenance of lingual epithelial tissue in the physiological state. However, the precise role of LESCs in generating tongue tumors and Bmi1-positive...

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Publicat a:Sci Rep
Autors principals: Tanaka, Toshihiro, Atsumi, Naho, Nakamura, Naohiro, Yanai, Hirotsugu, Komai, Yoshihiro, Omachi, Taichi, Tanaka, Kiyomichi, Ishigaki, Kazuhiko, Saiga, Kazuho, Ohsugi, Haruyuki, Tokuyama, Yoko, Imahashi, Yuki, Hisha, Hiroko, Yoshida, Naoko, Kumano, Keiki, Okazaki, Kazuichi, Ueno, Hiroo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177893/
https://ncbi.nlm.nih.gov/pubmed/28004815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39386
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