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A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples

Imputation using the 1000 Genomes haplotype reference panel has been widely adapted to estimate genotypes in genome wide association studies. To evaluate imputation quality with a relatively larger reference panel and a reference panel composed of different ethnic populations, we conducted imputatio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chou, Wen-Chi, Zheng, Hou-Feng, Cheng, Chia-Ho, Yan, Han, Wang, Li, Han, Fang, Richards, J. Brent, Karasik, David, Kiel, Douglas P., Hsu, Yi-Hsiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177868/
https://ncbi.nlm.nih.gov/pubmed/28004816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39313
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