Hepatocarcinogenesis in transgenic mice carrying hepatitis B virus pre-S/S gene with the sW172* mutation

Hepatitis B virus (HBV) carrying the rtA181T/sW172* mutation conferred cross-resistance to adefovir and lamivudine. Cell-based and clinical studies indicated that HBV carrying this mutation had an increased oncogenic potential. Herein, we created transgenic mouse models to study the oncogenicity of...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Lai, M-W, Liang, K-H, Lin, W-R, Huang, Y-H, Huang, S-F, Chen, T-C, Yeh, C-T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177775/
https://ncbi.nlm.nih.gov/pubmed/27918551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.77
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