A human gut ecosystem protects against C. difficile disease by targeting TcdA

BACKGROUND: A defined Microbial Ecosystem Therapeutic (MET-1, or “RePOOPulate”) derived from the feces of a healthy volunteer can cure recurrent C. difficile infection (rCDI) in humans. The mechanisms of action whereby healthy microbiota protect against rCDI remain unclear. Since C. difficile toxins...

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Detalhes bibliográficos
Publicado no:J Gastroenterol
Main Authors: Martz, Sarah Lynn, Guzman-Rodriguez, Mabel, He, Shu-Mei, Noordhof, Curtis, Hurlbut, David John, Gloor, Gregory Brian, Carlucci, Christian, Weese, Scott, Allen-Vercoe, Emma, Sun, Jun, Claud, Erika Chiong, Petrof, Elaine Olga
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177537/
https://ncbi.nlm.nih.gov/pubmed/27329502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-016-1232-y
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