The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetii

Coxiella burnetii is an intracellular bacterial pathogen that infects alveolar macrophages and replicates within a unique lysosome-derived vacuole. When Coxiella is trafficked to a host cell lysosome the essential Dot/Icm type IV secretion system is activated allowing over 130 bacterial effector pro...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Latomanski, Eleanor A., Newton, Patrice, Khoo, Chen Ai, Newton, Hayley J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176192/
https://ncbi.nlm.nih.gov/pubmed/28002452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006101
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