Transcriptional complexes engaged by apo-estrogen receptor-α isoforms have divergent outcomes

Unliganded (apo-) estrogen receptor α (ERα, NR3A1) is classically considered as transcriptionally unproductive. Reassessing this paradigm demonstrated that apo-human ERα (ERα66) and its N-terminally truncated isoform (ERα46) are both predominantly nuclear transcription factors that cycle on the endo...

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Detalhes bibliográficos
Main Authors: Métivier, Raphaël, Penot, Graziella, Carmouche, Richard P, Hübner, Michael R, Reid, George, Denger, Stefanie, Manu, Dominique, Brand, Heike, Koš, Martin, Benes, Vladimir, Gannon, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517616/
https://ncbi.nlm.nih.gov/pubmed/15343269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600377
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