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Transcriptional complexes engaged by apo-estrogen receptor-α isoforms have divergent outcomes
Unliganded (apo-) estrogen receptor α (ERα, NR3A1) is classically considered as transcriptionally unproductive. Reassessing this paradigm demonstrated that apo-human ERα (ERα66) and its N-terminally truncated isoform (ERα46) are both predominantly nuclear transcription factors that cycle on the endo...
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| Hoofdauteurs: | , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517616/ https://ncbi.nlm.nih.gov/pubmed/15343269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600377 |
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