Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3

Anti-silencing function 1 (ASF1) is a histone H3-H4 chaperone involved in DNA replication and repair, and transcriptional regulation. Here, we identify ASF1B, the mammalian paralog to ASF1, as a proliferation-inducing histone chaperone in human β-cells. Overexpression of ASF1B led to distinct transc...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Paul, Pradyut K., Rabaglia, Mary E., Wang, Chen-Yu, Stapleton, Donald S., Leng, Ning, Kendziorski, Christina, Lewis, Peter W., Keller, Mark P., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176155/
https://ncbi.nlm.nih.gov/pubmed/27753532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1241914
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