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Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358
Leucine-rich nuclear export signals (NESs) mediate rapid nuclear export of proteins via interaction with CRM1. This interaction is stimulated by RanGTP but remains of a relatively low affinity. In order to identify strong signals, we screened a 15-mer random peptide library for CRM1 binding, both in...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517610/ https://ncbi.nlm.nih.gov/pubmed/15329671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600370 |
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