Experimental Assessment of the Roles of Linear Plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the Infectious Cycle

Borrelia burgdorferi, which causes Lyme disease in humans, has an unusual genome composed of a linear chromosome and up to 21 extrachromosomal elements. Experimental data suggest that two of these elements, linear plasmids lp25 and lp28-1, play essential roles for infectivity in mice. In this study,...

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Autors principals: Grimm, Dorothee, Eggers, Christian H., Caimano, Melissa J., Tilly, Kit, Stewart, Philip E., Elias, Abdallah F., Radolf, Justin D., Rosa, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Bacterial Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC517563/
https://ncbi.nlm.nih.gov/pubmed/15385497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5938-5946.2004
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