Clonal Polymorphism of Borrelia burgdorferi Strain B31 MI: Implications for Mutagenesis in an Infectious Strain Background

A major obstacle to studying the functions of particular gene products in the mouse-tick infectious cycle of Borrelia burgdorferi has been an inability to knock out genes in pathogenic strains. Here, we investigated conditions for site-directed mutagenesis in B31 MI, the low-passage-number, infectio...

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Bibliographische Detailangaben
Hauptverfasser: Elias, Abdallah F., Stewart, Philip E., Grimm, Dorothee, Caimano, Melissa J., Eggers, Christian H., Tilly, Kit, Bono, James L., Akins, Darrin R., Radolf, Justin D., Schwan, Tom G., Rosa, Patricia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127854/
https://ncbi.nlm.nih.gov/pubmed/11895980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.2139-2150.2002
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