The Functions of the A1A2A3 Domains in Von Willebrand Factor Include Multimerin 1 Binding

Multimerin 1 (MMRN1) is a massive, homopolymeric protein that is stored in platelets and endothelial cells for activation-induced release. In vitro, MMRN1 binds to the outer surfaces of activated platelets and endothelial cells, the extracellular matrix (including collagen) and von Willebrand factor...

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Détails bibliographiques
Publié dans:Thromb Haemost
Auteurs principaux: Parker, D’Andra N., Tasneem, Subia, Farndale, Richard W., Bihan, Dominique, Sadler, J. Evan, Sebastian, Silvie, De Groot, Philip G., Hayward, Catherine P. M.
Format: Artigo
Langue:Inglês
Publié: Schattauer 2016
Sujets:
Cellular Haemostasis and Platelets
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175582/
https://ncbi.nlm.nih.gov/pubmed/27052467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH15-09-0700
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