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Protein phosphatase 1 abrogates IRF7-mediated type I IFN response in antiviral immunity
Interferon (IFN) regulatory factor 7 (IRF7) plays a key role in the production of IFNα in response to viral infection, and phosphorylation at IRF7 C-terminal serine sites is prelude to its function. However, no phosphatases which that may be involved in negatively regulate IRF7 phosphorylation and a...
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| Izdano u: | Eur J Immunol |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5175453/ https://ncbi.nlm.nih.gov/pubmed/27469204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646491 |
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