Distribution of Surface Protein Variants among Hyperinvasive Meningococci: Implications for Vaccine Design

The bacterium Neisseria meningitidis is a major cause of meningitis and septicemia worldwide. Outer membrane proteins (OMPs) are candidates in the search for comprehensive meningococcal vaccines; however, the formulation of OMP vaccines is complicated by antigenic diversity, which is generated by hi...

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Detalhes bibliográficos
Main Authors: Urwin, Rachel, Russell, Joanne E., Thompson, Emily A. L., Holmes, Edward C., Feavers, Ian M., Maiden, Martin C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517544/
https://ncbi.nlm.nih.gov/pubmed/15385499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5955-5962.2004
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