Potential of Recombinant Opa Proteins as Vaccine Candidates against Hyperinvasive Meningococci

Neisseria meningitidis causes half a million cases of septicemia and meningitis globally each year. The opacity (Opa) integral outer membrane proteins from N. meningitidis are polymorphic and highly immunogenic. Particular combinations of Opa proteins are associated with the hyperinvasive meningococ...

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Autori principali: Callaghan, M. J., Lewis, S., Sadarangani, M., Bailey, S. E. S., Chan, H., Ferguson, D. J. P., Derrick, J. P., Feavers, I., Maiden, M. C., Pollard, A. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191958/
https://ncbi.nlm.nih.gov/pubmed/21464082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01338-10
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