Potential of Recombinant Opa Proteins as Vaccine Candidates against Hyperinvasive Meningococci

Neisseria meningitidis causes half a million cases of septicemia and meningitis globally each year. The opacity (Opa) integral outer membrane proteins from N. meningitidis are polymorphic and highly immunogenic. Particular combinations of Opa proteins are associated with the hyperinvasive meningococ...

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Bibliographic Details
Main Authors: Callaghan, M. J., Lewis, S., Sadarangani, M., Bailey, S. E. S., Chan, H., Ferguson, D. J. P., Derrick, J. P., Feavers, I., Maiden, M. C., Pollard, A. J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191958/
https://ncbi.nlm.nih.gov/pubmed/21464082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01338-10
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