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Protein–DNA interfaces: a molecular dynamics analysis of time-dependent recognition processes for three transcription factors

We have studied the dynamics of three transcription factor–DNA complexes using all-atom, microsecond-scale MD simulations. In each case, the salt bridges and hydrogen bond interactions formed at the protein–DNA interface are found to be dynamic, with lifetimes typically in the range of tens to hundr...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Etheve, Loïc, Martin, Juliette, Lavery, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175364/
https://ncbi.nlm.nih.gov/pubmed/27658967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw841
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