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Structure and dynamics of DNA loops on nucleosomes studied with atomistic, microsecond-scale molecular dynamics

DNA loop formation on nucleosomes is strongly implicated in chromatin remodeling and occurs spontaneously in nucleosomes subjected to superhelical stress. The nature of such loops depends crucially on the balance between DNA deformation and DNA interaction with the nucleosome core. Currently, no hig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Pasi, Marco, Lavery, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914111/
https://ncbi.nlm.nih.gov/pubmed/27098037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw293
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